• Safety Rating of Actives
      The formulas in Hartz® UltraGuard® brand products for dogs combine two highly effective, active ingredients that both carry an EPA Overall Active Ingredient Safety Profile Designation of III:

      • Etofenprox also carries a Category IV EPA rating for both Acute Oral Toxicity and Acute Dermal Toxicity, the least toxic in its class.
      • Pryiproxifen, an insect growth regulator, is also rated as Category IV (least toxic) for Acute Oral Toxicity and a Category III rating for Acute Dermal Toxicity.
      • S-Methoprene, an insect growth regulator, is also rated as Category IV (least toxic) for Acute Oral Toxicity and a Category IV (least toxic) rating for Acute Dermal Toxicity.

      Active Ingredients in Canine Flea and Tick Products

      Table 1: Summary of Active Ingredients in Canine EPA-Registered Spot-On Flea and Tick Products

      Canine Chart